产品货号：
Z17968
中文名称：
HIF3A抗体
英文名称：
Anti-HIF3A Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HIF3A Antibody |
| 指标别名 | hypoxia inducible factor 3 subunit alpha;HIF-3A;HIF3-alpha-1;IPAS;MOP7;PASD7;bHLHe17;HIF3A |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | HIF3A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 575-600 of mouse Hif3 a (Hypoxia Inducible Factor). |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity-purified antibody is directed against mouse Hif3alpha protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.?A BLAST analysis was used to suggest cross-reactivity with Hif3a protein from mouse (100% homology) and rat (91% homology).Reactivity against human Hif3a is not expected as only 75% homology for the immunizing sequence is noted.No reactivity is expected against other forms of Hif proteins.Reactivity against homologues from other sources is not known. |
| 浓度 | 1.2mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | One of the most important factors in the cellular response to hypoxia is hypoxia-inducible factor (HIF),which transcriptionally activates genes encoding proteins that mediate adaptive responses to reduced oxygen availability.HIF is a member of the basic helix-loop-helix (bHLH) superfamily,in which the HLH domain mediates subunit dimerization while the basic domain binds to DNA.HIF binds to the hypoxia-responsive elements (HRE) located within the enhancer/promoter of hypoxia-inducible target genes and hence inhibits HRE-driven transcriptional activation.HIF target genes play critical roles in metabolism,angiogenesis,cell proliferation,and cell survival;in fact,HIF3-a may be a marker for tumor growth and apoptosis.Hif3 may participate in disorders with the cornea,lung,and heart.Anti-Hif3 alpha Antibody is useful for researchers interested in transcription factors,DNA binding,and Epilepsy research. |
| Uniprot ID | Q0VBL6 |
| 推荐稀释比 | ELISA:1:14,000 - 1:80,000 WB:1:1,000 - 1:8,000 |
相关搜索：HIF3A抗体，HIF3A多抗，Anti-HIF3A Antibody